Vol. 7, Issue 2, Part J (2025)

Effective medication administration is severely hampered by the ocular drug delivery barrier's complexity, which results in less than ideal therapeutic effects. Research is concentrating on new medications and delivery strategies to get around this problem, including the utilization of biodegradable formulations for ocular drug delivery technology. This involves investigating hydrogels, implants, biodegradable microneedles, and polymeric nanocarriers such liposomes, nanoparticles, nanosuspensions, nanomicelles, and nanoemulsions. The amount of recent research in these fields is growing quickly. In order to provide new treatment options for ocular conditions, this review summarizes the developments in biodegradable formulations for ocular drug delivery over the past ten years, assesses the clinical application of various biodegradable formulations in treating ocular diseases, and attempts to highlight future trends and their potential for useful clinical use.