Vol. 7, Issue 2, Part G (2025)

Sustained release formulations are currently regarded as one of the most significant novel systems for the formulation of essential drugs. The sustained release system exhibits greater therapeutic activity of a drug in comparison to immediate release. This technique has been utilized in an aqueous outer phase for numerous water-insoluble monomers, both with and without the drug. The bead polymerization technique represents an emerging variant of this system, which has attracted considerable attention in pharmaceutical research due to its capacity to sustain therapeutic drug levels, decrease dosing frequency, and improve patient compliance. This review study encompasses a detailed examination of the preparation and evaluation of sustained release beads utilizing both natural and synthetic polymers, along with their physical properties such as particle size, shape, surface morphology, and drug content. This review of the work will undoubtedly serve as a valuable resource for researchers and academicians in various capacities.