Vol. 7, Issue 2, Part C (2025)

This study investigates how medicinal plants cultivated under zero budget farming paradigms can be transformed into effective, low‑cost herbal medicines. The work encompasses three major segments: cultivation of medicinal species under Zero Budget Natural Farming (ZBNF) principles, development of simple extraction and formulation procedures suited for low infrastructure settings, and evaluation of safety, quality, and biological efficacy through in vitro and in vivo assays. We report that using ZBNF inputs like Jeevamrit significantly improves soil microbial and nutrient profiles, thereby enhancing biomass yield and phytochemical potential. Prototype formulations (aqueous‑ethanol extracts, syrups, topical gels) were standardized by marker assays and tested against bacterial pathogens and inflammatory models, showing promising inhibitory activity. No acute toxicity was found in preliminary animal tests. The results suggest that herbal medicines derived from zero budget farm produce can maintain acceptable quality and bioactivity, offering a pathway for decentralized, community‑level production of affordable phytomedicines.