Vol. 7, Issue 2, Part B (2025)

Lipid-based nanocarriers have become increasingly important in transdermal drug delivery due to their capacity to improve drug absorption, enable sustained release, and maintain drug stability. Systems such as liposomes, solid lipid nanoparticles, and nanostructured lipid carriers resemble natural cell membranes, which helps facilitate the passage of drugs through the skin barrier. Their ability to carry both water-soluble and fat-soluble drugs, combined with their biocompatibility, makes them highly adaptable for targeted therapeutic delivery. Improvements in formulation methods have enhanced their ability to penetrate the skin and increase treatment effectiveness. This summary underscores the potential of lipid-based nanocarriers as non-invasive and efficient platforms for delivering drugs through the skin, promoting innovative therapies with enhanced patient compliance.