Vol. 7, Issue 1, Part E (2025)

Microfluidics, a rapidly advancing field, has emerged as a promising technology in drug delivery systems, offering precise control over fluid dynamics at the microscale. This review explores the application of microfluidics in enhancing the efficacy and targeting of drug delivery. By enabling the manipulation of minute volumes of fluids, microfluidic devices facilitate controlled release, encapsulation and targeted delivery of therapeutic agents, improving drug bioavailability and reducing side effects. The integration of microfluidic technologies with various drug delivery platforms such as nanoparticles, liposomes and hydrogels has enabled the development of sophisticated systems that mimic biological processes, enhancing drug stability and release kinetics. The review also highlights the challenges associated with scaling up microfluidic systems for clinical applications, including fabrication complexity and material limitations. Finally, future perspectives on the use of microfluidics in personalized medicine and the potential for combining microfluidics with advanced technologies such as AI and nanomedicine are discussed. Overall, microfluidics holds significant promise for revolutionizing drug delivery, offering more effective, controlled and personalized therapeutic solutions.