Mahek, G Evangeli and Kaunain Fathema
Herbal pharmaceutics has gained significant attention due to the increasing demand for natural and bioactive compounds in modern medicine. Croton lechleri, commonly known as Dragon’s Blood, is a medicinal plant widely used in traditional medicine for its diverse pharmacological properties. This review provides a comprehensive analysis of the botanical characteristics, phytochemical profile, and therapeutic potential of Croton lechleri. The plant's bioactive compounds, including alkaloids, proanthocyanidins, taspine, and terpenes, contribute to its wound healing, anti-inflammatory, antimicrobial, antiviral, and antioxidant properties. Additionally, its gastrointestinal benefits, particularly in ulcer treatment and diarrhea management, have been explored. The article also highlights various pharmaceutical formulations, such as topical gels, oral suspensions, and advanced drug delivery systems like nanoparticles and liposomes, which enhance the bioavailability and efficacy of Croton lechleri-derived compounds. Furthermore, safety considerations, toxicological aspects, and regulatory perspectives are discussed. Despite its promising therapeutic applications, there is a need for further clinical studies to validate its efficacy and safety in pharmaceutical formulations. This review aims to provide valuable insights for researchers and pharmaceutical scientists exploring Croton lechleri as a potential candidate for novel herbal drug development.
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