Vol. 6, Issue 2, Part B (2024)

Polycystic ovarian syndrome (PCOS) is a prevalent hormonal disorder affecting women of reproductive age. It generally begins in youth, but symptoms might vary with time. PCOS can cause hormonal abnormalities, irregular menstrual cycles, elevated androgen levels, and ovarian cysts. Irregular periods, generally due to a lack of ovulation, might make it difficult to conceive. PCOS is the major cause of infertility. PCOS is a chronic disorder that cannot be healed. However, certain symptoms can be alleviated with lifestyle modifications, drugs, and fertility treatments. Phytosomes are complexes of phospholipids and naturally active phytochemicals bound in their structures, formed by the interaction of phosphatidylcholine (or any hydrophilic polar head groups) with plant extracts in an aprotic solvent. Phytosomes with balanced hydrophilicity and hydrophobicity may easily pass the bilipid cell membrane, increasing the bioavailability and absorption of water-soluble plant metabolites and boosting therapeutic efficacy. Phytosomes are safe to use and affordable in cost. There are two ways for preparing phyto-phospholipid complexes: solvent evaporation and anti-solvent precipitation. Solvent evaporation is a common process for producing phospholipid complexes, including phytosomes. Characterisation of Phytosomes Their characterization is based on physical properties such as form, size, distribution, drug, and chemical content.Phytosomes have several benefits, including improved medication absorption, anti-cancer and antioxidant properties, transdermal drug delivery, and wound rejuvenation.