Vol. 6, Issue 2, Part A (2024)

The abstract focuses on the transformative impact of innovations in personalized oral drug delivery systems, particularly how these technologies are enhancing therapeutic efficacy and improving patient compliance. The need for personalized medicine arises from the inherent variability in patients' genetics, metabolism, and disease states, which affect drug response. Tailoring drug formulations to individual needs is a major advancement in healthcare, especially as emerging technologies like 3D printing, smart polymers, and nanotechnology are now being integrated into pharmaceutical research. These innovations allow for highly customized drug delivery systems that can adjust drug release profiles based on specific patient parameters, ensuring that the drug acts in a manner suited to the individual's pharmacokinetics and pharmacodynamics.
The paper emphasizes that these technologies not only improve efficacy by enabling precise control over drug dosage and release timing but also enhance compliance by making medications more user-friendly-whether through simplified dosing regimens or multi-drug combination pills. The use of 3D printing allows for the creation of personalized pills with customized drug-release characteristics, while smart polymers respond to physiological stimuli, offering controlled release at desired locations in the body. Nanotechnology improves the bioavailability of poorly soluble drugs and enables targeted therapy, reducing side effects.