Rajia Sultana Nijhu, Ambia Khatun and Md. Farhad Hossen
In this review, we will discuss particle size analysis as it relates to specific pharmaceutical applications and regulatory aspects, fundamental principles, measurement techniques, and instrumentation types. We will cover the different types of measurement techniques that are commonly used in the pharmaceutical industry. This analysis is highly informative and will have a positive impact on the pharmaceutical field. Readers will gain a lot of knowledge from this review. Particle size is a critical process parameter in pharmaceutical production, as it can greatly affect the physical and chemical properties of drug substances and dosage forms. Particle size distribution (PSD) is one of the most important parameters to check when evaluating a new drug. Size reduction is a vital unit operation that is extensively used in pharmaceutical manufacturing. This process involves reducing large solid unit masses into small unit masses, coarse particles, or fine particles. Size reduction is also known as comminution, diminution, or pulverization.
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