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International Journal of Pharmaceutical Research and Development

Vol. 5, Issue 2, Part A (2023)

In vitro efficacy of an ayurvedic dentifrice against gingivitis causing pathogen

Author(s):

Jyoti Singh, Mahesh Katariya, Amit Sirdesai and Prasun Bandyopadhyay

Abstract:

Objective: The objective of this study was to study in vitro efficacy of Ayurvrdic herbs containing toothpaste against oral disease causing pathogens Porphyromonas gingivalis (P. gingivalis). The present study was designed to evaluate in efficacy of the Dabur Red paste containing Ayurvedic herbs like, Kalimirch, Pippali, Tomar, Sunthi, Lavang, Karpura & Pudina for prevention of gum diseases by inhibition of disease causing micro-organism P. gingivalis.
Material and Methods: The product was tested against microorganism’s P. gingivalis using agar well diffusion method. The agar-well diffusion method was used to test the antimicrobial effect. Inhibition zones formed around toothpastes after 24 hours of incubation were measured and the data collected were statistically analysed. The time-dependent killing assay was carried out on P. gingivalis. 
Conclusions: In vitro assessment of ayurvedic paste containing actives like, Kalimirch, Pippali, Tomar, Sunthi, Lavang, Karpura, Pudina and Gairica against gum disease causing oral pathogens revealed the 99.95 % germ kill efficacy of toothpaste against major gingivitis causing oral pathogen P. gingivalis in 2 min contact time.
 

Pages: 19-22  |  236 Views  87 Downloads


International Journal of Pharmaceutical Research and Development
How to cite this article:
Jyoti Singh, Mahesh Katariya, Amit Sirdesai and Prasun Bandyopadhyay. In vitro efficacy of an ayurvedic dentifrice against gingivitis causing pathogen. Int. J. Pharm. Res. Dev. 2023;5(2):19-22. DOI: 10.33545/26646862.2023.v5.i2a.35
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