International Journal of Pharmaceutical Research and Development

Vol. 3, Issue 1, Part A (2021)

Analytical techniques for the estimation of Celecoxib in capsule dosage form by spectrophotometric method

Author(s):

Kirtimaya Mishra, Snigdha Rani Behera, Soumyashree Tripathy, Biswa Ranjan Biswal, Chintapalli Gowri Sankar

Abstract:

For the determination of Celecoxib in pure formulations and its pharmaceutical formulations, a simple UV-spectrophotometric method was developed. Celecoxib exhibited maximum absorption at 244 nm in ethanol and obeyed linearity in the concentration range of 0.2-40 μg/ml. The method proposed was validated statistically. With good accuracy, all the proposed methods are simple, selective, reproducible, sensitive and precise. Some of the methods were proved to be superior to most of the reported methods. Many of these suggested prediction methods for chosen drugs, such as Celecoxib, have been successfully implemented either in bulk or in prescription formulations. The suggested methods can be used in bulk and prescription dosage formulations as alternative methods to the recorded ones for the routine determination of selected drugs in the sample.

Pages: 18-21  |  973 Views  406 Downloads

How to cite this article:
Kirtimaya Mishra, Snigdha Rani Behera, Soumyashree Tripathy, Biswa Ranjan Biswal, Chintapalli Gowri Sankar. Analytical techniques for the estimation of Celecoxib in capsule dosage form by spectrophotometric method. Int. J. Pharm. Res. Dev. 2021;3(1):18-21. DOI: 10.33545/26646862.2021.v3.i1a.21