International Journal of Pharmaceutical Research and Development

International Journal of Pharmaceutical Research and Development


International Journal of Pharmaceutical Research and Development
International Journal of Pharmaceutical Research and Development
2021, Vol. 3, Issue 1
Development of in-vitro in-vivo correlation of optimized fenofibrate tartaric acid co-crystal tablet

Ashwini Madgulkar, Mangesh Bhalekar, Anil Battase, Pravin Waghchaure, Sumedh Pradhan, Dhananjay Pagare

Fenofibrate an antilipidemic drug belonging to BCS class II, has very low oral bioavailability. Many approaches have been reported in literature and we selected a simple approach of formulating co-crystals to enhance the dissolution and subsequently bioavailability of fenofibrate. After reporting conformer screening, preparation and in-vitro evaluation of tartaric acid fenofibrate co-crystals as separate research work, formulation and in-vivo studies were undertaken in this work and an attempt to develop in-vitro in-vivo correlation was made using deconvolution and time scaling approach.
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How to cite this article:
Ashwini Madgulkar, Mangesh Bhalekar, Anil Battase, Pravin Waghchaure, Sumedh Pradhan, Dhananjay Pagare. Development of in-vitro in-vivo correlation of optimized fenofibrate tartaric acid co-crystal tablet. International Journal of Pharmaceutical Research and Development, Volume 3, Issue 1, 2021, Pages 07-14
International Journal of Pharmaceutical Research and Development International Journal of Pharmaceutical Research and Development