Mahewashsana A Pathan, Mahesh D Londhe, Dayanand R Jadhav
The Indian pharmaceutical industry is valued at Rs. 90000 crore and is growing at a rate of 12-14% annually. Exports are growing at a rate of 25% compound annual growth rate. The total exports of Pharma products is to extent of Rs. 40000 crore. India has also emerged as a hub for the clinical trials and drug discovery and development. Further more and more drug entities are being introduced which includes new chemical entities, Pharma products, vaccines, dosage forms, and new routes of administration and new therapeutic claims of existing drug moieties. The safe use of medicines is perhaps the single most important criteria that any regulatory authority within a given country has to ensure in order to protect the public health and the integrity of its health care system. Drug induced disease is defined as the unintended effect of a drug that results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical attention and/or to require hospitalization and may persist even after the offending drug has been withdrawn. Drug induced diseases also called as iatrogenic diseases, are well known but least studied entity. In this review, we have collected the information from review and research articles related to the drug induced diseases. This review is intended to aid the understanding of some basic concepts regarding the drug induced diseases. This tends to provide information about the some commonly occurring drug induced disorders, the drugs responsible for inducing disorders, their prevention and some of the treatments.